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Biomolecular Modelling |
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School of Biomedical Sciences |
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Research Skills & Training |
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Research Skills & Training |
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Computer Assisted Drug Design: Genome & proteome Sequence Analysis, protein structure modelling and validation, small molecule design using docking algorithms, pharmacophore models, lead optimization, QSAR and CoMFA analysis, modelling of protein-ligand interactions, protein-peptide and protein-protein interactions, free energy simulations, de-novo drug design, ab-inito predictions and designing peptide mimetics. Molecular Modelling and Bioinformatics: Genome Analysis, Proteome data analysis, DNA/ protein sequence analysis using GCG Wisconsin Package, Pharmacogenomics, data mining and metabolic pathways. Hands on experience with Insight-II, Cerius 2, AutoDock, AMBER, Gaussian, Discovery Studio and Triops-Sybyl6.9 and Schrodinger Packages. Experience in setting up Accelrys (Discovery Studio, Insight II) and Tripos Softwares on SGI and Linux. Experience in designing compound library database using ChemOffice. High Performance Computing: SGI Altix super-computers at IVEC (WA) and APAC (Canberra). |
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Research Skills |
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Certificate in Research Commercialisation (2008) Australian Technology Network of Universities. Certificate in Project Management (2007) Australian Technology Network of Universities. Certificate in Leadership and communication (2007) Australian Technology Network of Universities Advanced Certificate in Protein Structure Modelling (2001) GVK Bio Sciences Pvt. Ltd., Hyderabad, India. Advanced Certificate in Genomics and Proteomics (2002) GVK Bio Sciences Pvt. Ltd., Hyderabad, India. Accelrys qualified Level II Professional (2001). GVK Bio Sciences Pvt. Ltd., Hyderabad, India. |
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Training |
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Recombinant DNA technology, CPMB, Osmania Univeristy, Hyderabad. 2002. Homology Modelling of GPCR’s and Structure Based Drug Design, BioCampus, Hyderabad, conducted by Accelrys. 2002. Computer Systems Validation (GxP validation) at Zydus Research Center, conducted by Boehringer Ingelheim, Germany. 2002 Workshop on Molecular Modelling and Pharmainformatics, NIPER, Chandigarh. 2004 Workshop and Symposium on Role of Genomics and Proteomics, 2nd RBF Symposia. 2005 |
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Workshops |