Increasing the probability of
success while decreasing the time and cost to
market are major goals for the drug discovery
process. The WABRI Rapid Drug Discovery Program
(RDDP) utilises advanced Computer Aided Drug Design
(CADD) to accelerate the discovery process while
building in range of important fitness functions
to assist in the selection of compounds.
The Program relies on insightful observations
of common drug features and where these bind to
protein structures (at the "biophore"
site) to assist in the prediction of developable
drug molecules. The expected output of the project
is a rapid description of compounds that map to
specific sites on target proteins. Sample compounds
are applied for testing together with descriptions
of compounds fit.
Contact Details of Program Leader
Name: Prof Simon Carroll
Institution: WABRI - Curtin University
GPO Box U1987, Perth WA 6845
Phone: +61 8 9266 4822
Fax: +61 8 9266 7485
E-mail:
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